CCUS, formerly known as “CUPS,” is a disease of unknown cause. Clinical signs in dogs may include oral pain, foul breath, drooling and ulcers. These areas of ulceration include areas inside the mouth (lips and cheeks) that have contact with the teeth (“kissing ulcers”). In some cases, clinical signs may be controlled by vigorous home care, regular professional cleanings and medications. However, many dogs require either selective or extensive extraction of teeth. In the most severely affected areas, it is often necessary to surgically extract all teeth.